Butanoic acid, 2-[(2,3-dichlorophenyl)methylene]-3-oxo-, methyl ester → 1,4-Dihydro-2,6-dimethyl-3-methoxycarbonyl-4-(2,3-dichlorophenyl)-5-(2-phthalimidoethoxy)carbonyl-pyridine

Participants

Reaction Steps

Prepared by a method analogous to that of Example 1(a) from 13.0 g (48 mmol) of 2-(2,3-dichlorobenzylidene)-acetoacetic acid methyl ester and 13.1 g (48 mmol) of 3-amino-crotonic acid-(2-phthalimido ethyl)ester. 14.2 g (57%) of pale yellow crystals melting at 195°-196° C.

Provenance & Evidence