Hydrazine hydrate (1:1) → HCID 20132483, compound

HRID 845272Notes

Reaction equation

HRID 845272 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([CH3:44])=[C:5]([C:24]([O:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][N:33]2C(=O)C3=CC=CC=C3C2=O)=[O:25])[CH:6]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=2)[C:7]=1[C:8]([O:10][CH2:11][CH:12]([CH3:14])[CH3:13])=[O:9].O.NN>>[CH3:1][C:2]1[NH:3][C:4]([CH3:44])=[C:5]([C:24]([O:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][NH2:33])=[O:25])[CH:6]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([N+:21]([O-:23])=[O:22])[CH:16]=2)[C:7]=1[C:8]([O:10][CH2:11][CH:12]([CH3:14])[CH3:13])=[O:9]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20132455HCID 20132455, compound

Product 1

HCID 20132483HCID 20132483, compound

Procedure

Prepared by a method analogous to that of Example 1(b) from 13.28 g (22 mmol) of 1,4-dihydro-2,6-dimethyl-3-isobutoxycarbonyl-4-(3-nitrophenyl)-5-(6-phthalimidohexyloxy)carbonyl-pyridine and 3.3 ml (66 mmol) of hydrazine hydrate. 9.02 g (86%) of a yellow oil.

Sources & evidence

ORD record
ord-9d40e83524854a14a7750cbc6c1673bd
Source dataset
uspto-grants-1988_07
Patent number
US04757080

Reaction notes

Loading…