HRID845275

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)=O

HCID1536427

Methyl 2-[(3-nitrophenyl)methylene]-3-oxobutanoate

C12H11NO5

结构：C/C(N)=C/C(=O)OCCCCCCCCCCCN1C(=O)c2ccccc2C1=O

HCID67903688

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCCCCCCCCN2C(=O)c3ccccc3C2=O)C1c1cccc([N+](=O)[O-])c1

HCID20132490

未命名化合物

收率 98%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Prepared by a method analogous to that of Example 1(a) from 9.33 g (37.5 mmol) of 2-(3-nitrobenzylidene)-acetoacetic acid methyl ester and 15.00 g (37.5 mmol) of 3-amino-crotonic acid-(11-phthalimido-undecyl)ester. 23.18 g (98%) of yellow crystals, melting point 130°-132° C., obtained from methanol.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-61e341e2281a457cb5d5ada6e4335639
来源数据集: uspto-grants-1988_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04757080
来源说明: uspto-grants-1988_07

反应 SMILES

[CH3:1][O:2][C:3](=[O:18])[C:4](=[CH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[CH:10]=1)[C:5]([CH3:7])=O.[C:19]1(=[O:47])[N:23]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][O:35][C:36](=[O:41])/[CH:37]=[C:38](\[NH2:40])/[CH3:39])[C:22](=[O:42])[C:21]2=[CH:43][CH:44]=[CH:45][CH:46]=[C:20]12>CO>[CH3:7][C:5]1[NH:40][C:38]([CH3:39])=[C:37]([C:36]([O:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][N:23]2[C:19](=[O:47])[C:20]3=[CH:46][CH:45]=[CH:44][CH:43]=[C:21]3[C:22]2=[O:42])=[O:41])[CH:8]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[CH:10]=2)[C:4]=1[C:3]([O:2][CH3:1])=[O:18]