反应详情

Iron metal powder (13.4 g, 0.24 mole) was added portionwise to a solution of the nitro compound (22.9 g, 0.048 mole) from (b) in acetic acid (110 ml) and water (10 ml), heated on a steam bath. Heating was continued for a further 3 hours, after which the suspension was filtered hot through kieselguhr. The filtrate was poured into a mixture of ice/water (1 liter) with rapid stirring and the precipitate was collected by filtration to give the product as a white solid (20 g, 93%). m.p. 122°-124° C.

1. temperatureheated on a steam bath
2. temperatureHeating
3. filtrationafter which the suspension was filtered hot through kieselguhr
4. additionThe filtrate was poured into a mixture of ice/water (1 liter)
5. filtrationthe precipitate was collected by filtration