Ammonium Hydroxide → HCID 14183121, compound

HRID 845443Notes

Reaction equation

HRID 845443 reaction equation
[SH:1][C:2]1[S:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH3:13])[N:3]=1.[O-]Cl.[Na+].[OH-].[NH4+:18]>[OH-].[Na+].O>[CH3:13][C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[C:4]1[N:3]=[C:2]([S:1][NH2:18])[S:6][N:5]=1

Participants

6

Reactant 3

HCID 14923Ammonium HydroxideHCID 23665760Sodium HypochloriteHCID 178424214HCID 178424214, compound

Product 1

HCID 14183121HCID 14183121, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolvent2×HCID 14798Sodium HydroxideSolvent

Procedure

A solution of 56 g of 5-mercapto-3-(2-methylphenyl)-1,2,4-thiadiazole in 870 ml of 5% sodium hydroxide and 130 ml of water and a solution of 280 ml of 10% NaOCl diluted to 1000 ml with water were added dropwise to 2260 ml of an ammonium hydroxide solution while the mixture was stirred and maintained at 0° with an ice/methanol bath. The resulting mixture was stirred for 10 more minutes and the solids were collected, washed with water and dried under high vacuum (P2O5) to give 43 g of solid, m.p. 110°-112° C.

Workup

  1. temperaturemaintained at 0° with an ice/methanol bath
  2. stirringThe resulting mixture was stirred for 10 more minutes
  3. customthe solids were collected
  4. washwashed with water
  5. dry with materialdried under high vacuum (P2O5)

Sources & evidence

ORD record
ord-e2cd02c35c154f35a36bef5b10af7e57
Source dataset
uspto-grants-1988_07
Patent number
US04758578

Reaction notes

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