Ammonium Hydroxide → HCID 14183125, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 41 g of 5-mercapto-3-(3-chlorophenyl)-1,2,4-thiadiazole in 602 ml of 5% sodium hydroxide and a solution prepared by diluting 378 ml of 5.25% NaOCl to 602 ml with water were added dropwise simultaneously to 1634 ml of ammonium hydroxide solution while maintaining the mixture at 0° C. with a salt/ice bath. The resulting mixture was stirred for 30 minutes and the solids were collected, washed with water and dried under vacuum (with P2O5) to give 5.4 g of solid, m.p.>150° dec.

Provenance & Evidence