Ammonium Hydroxide → HCID 14183125, compound

HRID 845448Notes

Reaction equation

HRID 845448 reaction equation
[SH:1][C:2]1[S:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[CH:8]=2)[N:3]=1.[O-]Cl.[Na+].[OH-].[NH4+:18]>[OH-].[Na+].O>[Cl:13][C:9]1[CH:8]=[C:7]([C:4]2[N:3]=[C:2]([S:1][NH2:18])[S:6][N:5]=2)[CH:12]=[CH:11][CH:10]=1

Participants

6

Reactant 3

HCID 14923Ammonium HydroxideHCID 23665760Sodium HypochloriteHCID 178527833HCID 178527833, compound

Product 1

HCID 14183125HCID 14183125, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 14798Sodium HydroxideSolvent

Conditions

Temperature
0 °C

Procedure

A solution of 41 g of 5-mercapto-3-(3-chlorophenyl)-1,2,4-thiadiazole in 602 ml of 5% sodium hydroxide and a solution prepared by diluting 378 ml of 5.25% NaOCl to 602 ml with water were added dropwise simultaneously to 1634 ml of ammonium hydroxide solution while maintaining the mixture at 0° C. with a salt/ice bath. The resulting mixture was stirred for 30 minutes and the solids were collected, washed with water and dried under vacuum (with P2O5) to give 5.4 g of solid, m.p.>150° dec.

Workup

  1. customthe solids were collected
  2. washwashed with water
  3. dry with materialdried under vacuum (with P2O5)

Sources & evidence

ORD record
ord-1bc5c5c1e0f446f49bf6464d6ba8cc81
Source dataset
uspto-grants-1988_07
Patent number
US04758578

Reaction notes

Loading…