HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 86742274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | HCID 86742270 | HCID 86742270 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86742274 | HCID 86742274 | — |
Reaction Steps
A solution of cis-decahydro-2-oxo-1H-cycloocta[b]pyrrole-1-acetic acid ethyl ester (4.0 g, 0.0157 mole) in methanol (30 ml) is saturated with anhydrous ammonia. The solution is stirred 18 hours. The solution is concentrated at reduced pressure to yield a solid. Trituration with anhydrous diethyl ether yields pure cis-decahydro-2-oxo-1H-cycloocta[b]pyrrole-1-acetamide with mp 110°-112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04758585 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-9c153175249c4b66814348464bcb464f |
| Source note | uspto-grants-1988_07 |