Hydrazine hydrate (1:1) → HCID 131715640, compound

HRID 845671Notes

Reaction equation

HRID 845671 reaction equation
[NH:1]([C:31]([O:33][C:34]([CH3:37])([CH3:36])[CH3:35])=[O:32])[C@H:2]([C:5]([NH:7][C@H:8]([C:13]([NH:15][C@H:16]([C:21]([NH:23][C@H:24]([C:27]([O:29]C)=O)[CH2:25][OH:26])=[O:22])[CH2:17][CH:18]([CH3:20])[CH3:19])=[O:14])[CH2:9][C:10](=[O:12])[NH2:11])=[O:6])[CH2:3][OH:4].O.[NH2:39][NH2:40]>>[NH:1]([C:31]([O:33][C:34]([CH3:36])([CH3:35])[CH3:37])=[O:32])[C@H:2]([C:5]([NH:7][C@H:8]([C:13]([NH:15][C@H:16]([C:21]([NH:23][C@H:24]([C:27]([NH:39][NH2:40])=[O:29])[CH2:25][OH:26])=[O:22])[CH2:17][CH:18]([CH3:20])[CH3:19])=[O:14])[CH2:9][C:10](=[O:12])[NH2:11])=[O:6])[CH2:3][OH:4]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 13875654HCID 13875654, compound

Product 1

HCID 131715640HCID 131715640, compound

Procedure

17 g of Boc-Ser-Asn-Leu-Ser-OMe are dissolved in 200 ml of hydrazine hydrate, stirred for 2 hours at 20°, and evaporated to dryness at 25°. The residue is washed with diethylether, dried, and the title compound is obtained.

Workup

  1. customevaporated to dryness at 25°
  2. washThe residue is washed with diethylether
  3. customdried

Sources & evidence

ORD record
ord-a516618ea8c0415eb3f7b1cc6b0a9e1d
Source dataset
uspto-grants-1988_07
Patent number
US04758550

Reaction notes

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