Potassium Carbonate → HCID 13913533, compound

Participants

Reaction Steps

1-(4-Acetoxybenzyl)-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydrocarbostyril (2 g) was dissolved in methanol (20 ml). To the solution was added a solution of potassium carbonate (1.53 g) in water (20 ml) and the mixture was stirred at room temperature for 30 minutes. After completion of reaction, the reaction mixture was poured into water and extracted with chloroform. The extract was washed with saturated saline solution, dried over magnesium sulfate and evaporated under reduced pressure. The residue was recrystallized from ethanol to give 1-(4-hydroxybenzyl)-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydrocarbostyril (950 mg).

Provenance & Evidence