Hydrogen Peroxide → HCID 54729490, compound

HRID 845818Notes

Reaction equation

HRID 845818 reaction equation
[OH:1][C:2]1[C:3]2[CH:27]=[C:26]([S:28][CH3:29])[CH:25]=[CH:24][C:4]=2[S:5][C:6]=1[C:7]([NH:9][CH:10]=[C:11]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:8].[OH:30]O>C(O)(=O)C>[OH:1][C:2]1[C:3]2[CH:27]=[C:26]([S:28]([CH3:29])=[O:30])[CH:25]=[CH:24][C:4]=2[S:5][C:6]=1[C:7]([NH:9][CH:10]=[C:11]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)=[O:8]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 54680206HCID 54680206, compound

Product 1

HCID 54729490HCID 54729490, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 3-hydroxy-5-methylthio-N-(2,2-diphenylethenyl)-benzo[b]thiophene-2-carboxamide (0.42 g, 0.0010 moles) and 30% H2O2 (0.80 ml) in acetic acid (10 ml) was stirred at 75° for 30 minutes. The reaction was cooled to 0° and the yellow precipitate was filtered, acetic acid washed and dried under vacuum, to afford 0.38 g (88%) of 3-hydroxy-N-(2,2-diphenyl)ethenyl-5-methylsulfinylbenzo[b]thiophene-2-carboxamide. MS gave Mol ion at 433.

Workup

  1. temperatureThe reaction was cooled to 0°
  2. filtrationthe yellow precipitate was filtered
  3. washacetic acid washed
  4. customdried under vacuum

Sources & evidence

ORD record
ord-e5907486fa944e9e95cd87005f48b14f
Source dataset
uspto-grants-1988_07
Patent number
US04760086

Reaction notes

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