Sodium → HCID 20130664, compound

HRID 845920Notes

Reaction equation

HRID 845920 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:11]([NH:14][C:15]([NH:17][C:18]2[CH2:22][CH2:21][CH2:20][C:19]=2[C:23]([O:25]CC)=O)=[S:16])=[CH:10][C:3]=1[C:4]([O:6][CH:7]([CH3:9])[CH3:8])=[O:5].[Na]>C(O)(C)C.CN(C)C=O>[Cl:1][C:2]1[CH:13]=[CH:12][C:11]([N:14]2[C:23](=[O:25])[C:19]3[CH2:20][CH2:21][CH2:22][C:18]=3[NH:17][C:15]2=[S:16])=[CH:10][C:3]=1[C:4]([O:6][CH:7]([CH3:9])[CH3:8])=[O:5]

Participants

4

Reactant 2

HCID 5360545SodiumHCID 54254244HCID 54254244, compound

Product 1

HCID 20130664HCID 20130664, compound

Reagents, catalysts & solvents 1

HCID 20197112Isopropanol dimethylformamideSolvent

Procedure

using isopropyl 2-chloro-5-{3-[2-(ethoxycarbonyl)-1-cyclopenten-1-yl]thioureido}-benzoate with sodium isopropylate in an isopropanol/dimethylformamide mixture there is obtained isopropyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-4-oxo-2-thioxo-3H-cyclopenta[d]pyrimidin-3-yl)benzoate.

Sources & evidence

ORD record
ord-a4133343807e422a880b910e22a14089
Source dataset
uspto-grants-1988_07
Patent number
US04760163

Reaction notes

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