Methyl iodide → HCID 20130625, compound

HRID 845965Notes

Reaction equation

HRID 845965 reaction equation
[Cl:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]2[C:18](=[O:19])[C:17]3[CH2:20][CH2:21][CH2:22][C:16]=3[N:15]([CH3:23])[C:14]2=[O:24])=[CH:9][C:3]=1[C:4]([O:6][CH2:7]C)=[O:5].[Na].ClC1C=CC(N2C(=O)C3CCCCC=3N(C)C2=O)=CC=1C(O)=O.CI>>[Cl:1][C:2]1[CH:12]=[CH:11][C:10]([N:13]2[C:18](=[O:19])[C:17]3[CH2:20][CH2:21][CH2:22][C:16]=3[N:15]([CH3:23])[C:14]2=[O:24])=[CH:9][C:3]=1[C:4]([O:6][CH3:7])=[O:5]

Participants

5

Reactant 4

HCID 6328Methyl iodideHCID 5360545SodiumHCID 20130616ethyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-1-methyl-2,4-dioxo-3H-cyclopenta[d] pyrimidin-3-yl)-benzoateHCID 20130662HCID 20130662, compound

Product 1

HCID 20130625HCID 20130625, compound

Procedure

using ethyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-1-methyl-2,4-dioxo-3H-cyclopenta[d]pyrimidin-3-yl)-benzoate via the sodium salt of the corresponding carboxylic acid and methyl iodide there is obtained methyl 2-chloro-5-(1,2,4,5,6,7-hexahydro-1-methyl-2,4-dioxo-3H-cyclopenta[d]pyrimidin-3-yl)-benzoate, m.p. 164°-166° C.,

Sources & evidence

ORD record
ord-bb1e39201af04e659caeeb591cd11a0b
Source dataset
uspto-grants-1988_07
Patent number
US04760163

Reaction notes

Loading…