Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 845978Generated: October 26, 2026

3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester → Ethyl 2-chloro-5-{3-[4-(methoxycarbonyl)-2,5-dihydro-thien-3-yl]ureido}-benzoate

https://huagongshe.com/reaction/845978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl esterHCID 98424—
ReactantEthyl 2-chloro-5-ureidobenzoateHCID 21270735—
ProductEthyl 2-chloro-5-{3-[4-(methoxycarbonyl)-2,5-dihydro-thien-3-yl]ureido}-benzoateHCID 20130667—

Reaction Steps

using ethyl 2-chloro-5-ureidobenzoate and methyl 3-oxotetrahydrothiophene-4-carboxylate there is obtained ethyl 2-chloro-5-{3-[4-(methoxycarbonyl)-2,5-dihydro-thien-3-yl]ureido}-benzoate

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04760163
Source datasetuspto-grants-1988_07
ORD IDord-ecbd5d5cf0234dfe85029adfdcf1e4f3
Source noteuspto-grants-1988_07