1,1'-Carbonyldiimidazole → HCID 178474866, compound

Participants

Reaction Steps

To a solution of 580 mg (2.0 mmol) of 6-(3-amino-4-acetylaminoethylamino-phenyl)-4,5-dihydro-3(2H)-pyridazinone in 50 ml of dimethylformamide, 325 mg (2.0 mmol) of carbonyldiimidazole are added at 50° C. After 45 minutes at 50° C. the mixture is evaporated to dryness and the residue is mixed with 10 ml of water. The product precipitated is suction filtered, washed with 5 ml of water and dried.

Provenance & Evidence