HCID 14884394, compound → HCID 14884402, compound

Participants

Reaction Steps

30.0 g (70.7 mmol) of 6-[4-(3-phthalimidopropylsulphonyl)phenyl]-4,5-dihydro-3(2H)-pyridazinone are stirred vigorously for two hours at ambient temperature in a mixture of 200 ml of toluene and 300 ml of 40% aqueous methylamine solution. Then the solid matter precipitated is suction filtered, washed successively with 100 ml of water, 50 ml of acetone and 50 ml of diethylether and then dried over phosphorus pentoxide in a vacuum drying cupboard.

Provenance & Evidence