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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846138Generated: October 31, 2026

((o-Allylphenoxy)methyl)oxirane → 6-[2-[2-[3-(2-Allyl-phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone

https://huagongshe.com/reaction/846138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant((o-Allylphenoxy)methyl)oxiraneHCID 98437—
Reactant6-[2-(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-5-methyl-3(2H)-pyridazinoneHCID 14404065—
Product6-[2-[2-[3-(2-Allyl-phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-4,5-dihydro-5-methyl-3(2H)-pyridazinoneHCID 15107847—

Reaction Steps

Prepared analogously to Example 1 from 1-(2-allylphenoxy)-2,3-epoxypropane and 6-[2-(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-5-methyl-3(2H)- pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-418aa36be80e4e009409e0040c508989
Source noteuspto-grants-1992_08