Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846142Generated: October 30, 2026

1-(4-Methylsulphonyloxy-phenoxy)-2,3-epoxypropane → 6-[1-[2-[3-(4-Methylsulphonyloxy-phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinone

https://huagongshe.com/reaction/846142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Methylsulphonyloxy-phenoxy)-2,3-epoxypropaneHCID 11550507—
Reactant6-[1-(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinoneHCID 15107853—
Product6-[1-[2-[3-(4-Methylsulphonyloxy-phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinoneHCID 15107855—

Reaction Steps

Prepared analogously to Example 1 from 1-(4-methylsulphonyloxy-phenoxy)-2,3-epoxypropane and 6-[1(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-23451f168f5043468ba4c5f6cb105064
Source noteuspto-grants-1992_08