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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846144Generated: November 1, 2026

1-[4-(2-Isobutoxyethyl)phenoxy]-2,3-epoxypropane → 6-[1-[3-[3-(4-(2-Isobutoxyethyl)phenoxy)-2hydroxypropylamino]propyl]benzimidazol-5-yl]-4,5-dihydro-3-(2H)-pyridazinone

https://huagongshe.com/reaction/846144

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(2-Isobutoxyethyl)phenoxy]-2,3-epoxypropaneHCID 15107806—
Reactant6-[1-(3-aminopropyl)benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinoneHCID 15107856—
Product6-[1-[3-[3-(4-(2-Isobutoxyethyl)phenoxy)-2hydroxypropylamino]propyl]benzimidazol-5-yl]-4,5-dihydro-3-(2H)-pyridazinoneHCID 14884447—

Reaction Steps

Prepared analogously to Example 1 from 1-[4-(2-isobutoxyethyl)-phenoxy]-2,3-epoxypropane and 6-[1-(3-aminopropyl)benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-47ceee108c144f6ea1e987c31b69c34a
Source noteuspto-grants-1992_08