2-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxirane → HCID 15107869, compound

HRID 846156Notes

Reaction equation

HRID 846156 reaction equation
[CH:1]1([CH2:5][O:6][CH2:7][CH2:8][C:9]2[CH:19]=[CH:18][C:12]([O:13][CH2:14][CH:15]3[O:17][CH2:16]3)=[CH:11][CH:10]=2)[CH2:4][CH2:3][CH2:2]1.[NH2:20][CH2:21][CH2:22][N:23]1[C:27]2[CH:28]=[CH:29][C:30]([C:32]3[CH:33]=[CH:34][C:35](=[O:38])[NH:36][N:37]=3)=[CH:31][C:26]=2[N:25]=[CH:24]1>>[CH:1]1([CH2:5][O:6][CH2:7][CH2:8][C:9]2[CH:19]=[CH:18][C:12]([O:13][CH2:14][CH:15]([OH:17])[CH2:16][NH:20][CH2:21][CH2:22][N:23]3[C:27]4[CH:28]=[CH:29][C:30]([C:32]5[CH:33]=[CH:34][C:35](=[O:38])[NH:36][N:37]=5)=[CH:31][C:26]=4[N:25]=[CH:24]3)=[CH:11][CH:10]=2)[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 151078052-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxiraneHCID 151078176-[1-(2-Aminoethyl)benzimidazol-5-yl]-3(2H)-pyridazinone

Product 1

HCID 15107869HCID 15107869, compound

Procedure

Prepared analogously to Example 1 from 1-[4-(2-cyclobutylmethoxyethyl)phenoxy]-2,3-epoxypropane and 6-[1-(2-aminoethyl)benzimidazol-5-yl]-3(2H)-pyridazinone.

Sources & evidence

ORD record
ord-ea6d072340e34044be5a327b64b59b8a
Source dataset
uspto-grants-1992_08
Patent number
US05135932

Reaction notes

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