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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 846156Generated: November 1, 2026

2-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxirane → 6-[1-[2-[3-(4-(2-Cyclobutylmethoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-3(2H)-pyridazinone

https://huagongshe.com/reaction/846156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxiraneHCID 15107805—
Reactant6-[1-(2-Aminoethyl)benzimidazol-5-yl]-3(2H)-pyridazinoneHCID 15107817—
Product6-[1-[2-[3-(4-(2-Cyclobutylmethoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-3(2H)-pyridazinoneHCID 15107869—

Reaction Steps

Prepared analogously to Example 1 from 1-[4-(2-cyclobutylmethoxyethyl)phenoxy]-2,3-epoxypropane and 6-[1-(2-aminoethyl)benzimidazol-5-yl]-3(2H)-pyridazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05135932
Source datasetuspto-grants-1992_08
ORD IDord-ea6d072340e34044be5a327b64b59b8a
Source noteuspto-grants-1992_08