Methyl iodide → HCID 19885224, compound

Participants

Reaction Steps

To an ether solution containing 1.0 g of 4-butoxy-N,N,α-trimethylbenzenepropanamine (the free base of the compound prepared in Example 41B) was added 2.5 ml of iodomethane and, over a period of 4 hours an oil separated from the solution. The solvent was evaporated and the residue was crystallized from ethyl acetate to give 0.48 g (31% yield) of the desired titled compound, m.p. 160°-165° C.

Provenance & Evidence