反应详情

温度

40 °C

137.1 g (1.0 mol) of o-nitrotoluene are added dropwise to 535.9 g (4.6 mol) of chlorosulfonic acid and 2 g of sulfamic acid such that the temperature does not exceed 40° C. The mixture is then stirred at 40° C. for 1 hour and slowly heated to 105° C. It is then stirred at 105° C. for 6 hours, cooled and added dropwise to ice water at 0 to 5° C. The precipitated crystals are filtered off with suction and washed with ice water. 236.1 g of 2-nitrotoluene-4-sulfonyl chloride (water content 10.8%), corresponding to 210.6 g (89% of theory), having a melting point of 40° C. are obtained.

1. customdoes not exceed 40° C
2. temperatureslowly heated to 105° C
3. stirringIt is then stirred at 105° C. for 6 hours
4. temperaturecooled
5. filtrationThe precipitated crystals are filtered off with suction
6. washwashed with ice water
7. customare obtained