1,3-Dichloro-2-propanol → 1,3-Bis[(2-hydroxyethyl)phenylamino]-2-propanol

HRID 846533Notes

Reaction equation

HRID 846533 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[C:11](=[O:14])([O-])[O-].[Ca+2].Cl[CH2:17][CH:18]([OH:21])[CH2:19]Cl>O>[OH:1][CH2:2][CH2:3][N:4]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:17][CH:18]([OH:21])[CH2:19][N:4]([CH2:3][CH2:11][OH:14])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

5

Reactant 3

HCID 72891,3-Dichloro-2-propanolHCID 10112Calcium CarbonateHCID 31235N-(2-Hydroxyethyl)aniline

Product 1

HCID 159261861,3-Bis[(2-hydroxyethyl)phenylamino]-2-propanol

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The mixture consisting of 2 moles (274.4 g) of N-β-hydroxyethylaniline, 140 g of calcium carbonate and 1.2 moles (154.8 g) of 1,3-dichloro-2-propanol in 1 liter of water is heated for 6 hours under water reflux.

Workup

  1. temperatureis heated for 6 hours under water
  2. temperaturereflux

Sources & evidence

ORD record
ord-c963fcf93c1c49f8911e1659edd05143
Source dataset
uspto-grants-1992_08
Patent number
US05137538

Reaction notes

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