反应详情

Into a flask were charged 151.0 mg (0.58 mmol) of 4-(2-methyloctanoyl) benzoic acid, 321.3 mg (1.74 mmol) of p,p'-biphenol, N,N'-dicyclohexyl-carbodiimide (0.66 mmol) and 6 ml of dried pyridine, which was stirred at room temperature for 6 hours. The resulting solid was filtered off and the solvent was distilled off, and the resulting oily matter was purified by a column chromatography of silica gel to obtain 122.3 mg (yield 49%) of 4-(2-methyloctanoyl) benzoic acid-4-hydroxy biphenyl.

1. filtrationThe resulting solid was filtered off
2. distillationthe solvent was distilled off
3. customthe resulting oily matter was purified by a column chromatography of silica gel