3-Fluorophenol → HCID 15096980, compound

HRID 846762Notes

Reaction equation

HRID 846762 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.[CH:9]1([C:12](Cl)=[O:13])[CH2:11][CH2:10]1>>[F:1][C:2]1[CH:3]=[C:4]([O:8][C:12]([CH:9]2[CH2:11][CH2:10]2)=[O:13])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 97433-FluorophenolHCID 77637Cyclopropanecarbonyl chloride

Product 1

HCID 15096980HCID 15096980, compoundYield 98%

Conditions

Temperature
80 °C

Procedure

To 31.4 parts of 3-fluorophenol were added dropwise 29.3 parts of cyclopropanecarbonyl chloride at 80° C. Upon completion, the whole was stirred for 1 hour at 80° C. The reaction mixture was distilled, yielding 49.7 parts (98%) of (3-fluorophenyl)cyclopropanecarboxylate; bp. 75°-85° C. at 0.5 mm. pressure (intermediate 86).

Workup

  1. distillationThe reaction mixture was distilled

Sources & evidence

ORD record
ord-005c5779bdd04e7e821f8c25f3f0b21a
Source dataset
uspto-grants-1992_08
Patent number
US05137896

Reaction notes

Loading…