1-Iodopropane → HCID 86746070, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 17 starting with 2-amino-4-(4-chlorophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine dihydrochloride (4.0 g, 13.5 mmol) and iodopropane (1.3 mL, 13.5 mmol) instead of iodoethane to produce 2.1 g (51%) of 2-amino-4-(4-chlorophenyl)-6-propyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine dihydrochloride 1/4 hydrate. m.p. 244°-246° C. MS: 303(HM+).

Provenance & Evidence