1-Chloro-2-(diethylamine)ethane hydrochloride → HCID 19883256, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 17 starting with 2-amino-4-(4-fluorophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (2.0 g, 8.2 mmol) and diethylaminoethylchloride hydrochloride (2.8 g, 16.4 mmol) to give 1.1 g (39%) of 2-amino-5-(2- diethylaminoethyl)-4-(4-fluorophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine trihydrochloride. m.p. 234°-236° C. MS: 343(MH+).

Provenance & Evidence