N-1-Naphthylethylenediamine dihydrochloride → N-(1-Naphthyl)ethylenediamine

HRID 846835Notes

Reaction equation

HRID 846835 reaction equation
Cl.Cl.[C:3]1([NH:13][CH2:14][CH2:15][NH2:16])[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=1.C(=O)([O-])O.[Na+]>C(Cl)(Cl)Cl>[C:3]1([NH:13][CH2:14][CH2:15][NH2:16])[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 15106N-1-Naphthylethylenediamine dihydrochlorideHCID 516892Sodium Bicarbonate

Product 1

HCID 15107N-(1-Naphthyl)ethylenediamineYield 57.8%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a suspension of N-1-naphthylethylenediamine dihydrochloride (746 mg, 2.88 mmol) in chloroform (50 ml), a saturated solution of sodium hydrogen carbonate (50 ml) was added, and the resultant mixture was stirred. The organic layer was collected, washed with a saturated solution of sodium chloride twice, dried over anhydrous sodium sulfate and concentrated to give Compound (7) (310 mg) as an oil. Yield, 58%.

Workup

  1. customThe organic layer was collected
  2. washwashed with a saturated solution of sodium chloride twice
  3. dry with materialdried over anhydrous sodium sulfate
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-08db69fa5e3d4f0d9628bbfdb3294287
Source dataset
uspto-grants-1992_08
Patent number
US05138039

Reaction notes

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