Potassium Hydroxide → (4,6-Diisopropyl-1,3-phenylene)dimethanol

HRID 846879Notes

Reaction equation

HRID 846879 reaction equation
C([O:4][CH2:5][C:6]1[CH:11]=[C:10]([CH2:12][O:13]C(=O)C)[C:9]([CH:17]([CH3:19])[CH3:18])=[CH:8][C:7]=1[CH:20]([CH3:22])[CH3:21])(=O)C.[OH-].[K+]>CO>[OH:4][CH2:5][C:6]1[CH:11]=[C:10]([CH2:12][OH:13])[C:9]([CH:17]([CH3:18])[CH3:19])=[CH:8][C:7]=1[CH:20]([CH3:22])[CH3:21]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 148505442,4-Bis-(acetoxymethyl)-1,5-diisopropylbenzene

Product 1

HCID 14850545(4,6-Diisopropyl-1,3-phenylene)dimethanol

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

40.2 g (131 mmol) of the compound from Example 2 are stirred at 50° C. for 3 h with 16.1 g (0.3 mol) of potassium hydroxide in 200 ml of methanol. After distilling off the solvent, the residue is taken up in ether, washed with water, dried using sodium sulphate and recrystallized from ethyl acetate/petroleum ether.

Workup

  1. distillationAfter distilling off the solvent
  2. washwashed with water
  3. customdried
  4. customrecrystallized from ethyl acetate/petroleum ether

Sources & evidence

ORD record
ord-df88671860084510912e9327b15a7a7a
Source dataset
uspto-grants-1992_08
Patent number
US05138090

Reaction notes

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