HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 3-(3-Iodopropylsulfonylamino)-2-methylcarbamoyloxy-1-octadecylcarbamoyloxypropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane | HCID 14835023 | — |
| Reactant | 3-(3-Chloropropylsulfonylamino)-2-methylcarbamoyloxy-1-octadecylcarbamoyloxypropane | HCID 14835039 | — |
| Reactant | 1-Hexadecylthio-2-methylcarbamoyloxy-3-trityloxypropane | HCID 19884201 | — |
| Product | 3-(3-Iodopropylsulfonylamino)-2-methylcarbamoyloxy-1-octadecylcarbamoyloxypropane | HCID 15667293 | — |
Reaction Steps
3-(3-Chloropropylsulfonylamino)-2-methylcarbamoyloxy-1-octadecylcarbamoyloxypropane III c2 is allowed to react and worked up by the same procedure as described in (5). m.p. 97°-99° C. The summary of the experimental condition and the physical data of the product are listed in the Table 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05138067 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-681ae825374b46959d3857d1f8caef89 |
| Source note | uspto-grants-1992_08 |