HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-Cyanomethyl-3-octadecylcarbamoyloxypropyl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 2-Cyanomethyl-3-octadecylcarbamoyloxypropanol | HCID 14834995 | — |
| Reactant | 3-Azido-1-hexadecylthio-2-methoxycarbonylaminopropane | HCID 14835094 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Cyanomethyl-3-octadecylcarbamoyloxypropyl methanesulfonate | HCID 19884186 | — |
Reaction Steps
A mixture of 940 mg (2.29 mM) of 2-cyanomethyl-3-octadecylcarbamoyloxypropanol V n2, 0.231 ml (2.98 mM) of methanesulfonyl chloride and 0.483 ml (3.44 mM) of triethylamine in 10 ml of dichloromethane is allowed to react by the same procedure as described in (52) and crude product of the titled compound V n2a is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05138067 |
| Source dataset | uspto-grants-1992_08 |
| ORD ID | ord-a43b87eda0ac42aca3087f07cafc0939 |
| Source note | uspto-grants-1992_08 |