2-(4-Tert-butylphenoxy)acetic acid → 4-tert-Butylphenoxyacetyl chloride

HRID 847123Notes

Reaction equation

HRID 847123 reaction equation
[C:1]([C:5]1[CH:15]=[CH:14][C:8]([O:9][CH2:10][C:11](O)=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].S(Cl)([Cl:18])=O>>[C:1]([C:5]1[CH:15]=[CH:14][C:8]([O:9][CH2:10][C:11]([Cl:18])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 157182-(4-Tert-butylphenoxy)acetic acidHCID 24386Thionyl Chloride

Product 1

HCID 6111954-tert-Butylphenoxyacetyl chloride

Procedure

Filling in a dry 250 ml flask respectively 57.42 g (0.276 mol) of para-t-butylphenoxyacetic acid synthesized in Example 17 and 80.5 ml of thionyl chloride, the reaction mixture was heated and refluxed for 5-6 hours.

Workup

  1. temperaturerefluxed for 5-6 hours

Sources & evidence

ORD record
ord-b8383f0a2ee648a49bd2fc6b75370584
Source dataset
uspto-grants-1992_08
Patent number
US05139564

Reaction notes

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