反应详情

During one hour and while stirring, a solution of 0.14 mole of sodium nitrite in 30 ml water is added to a cold solution (0°-5° C.) of 0.14 mole of 6-hydroxy quinazolin, 12 ml concentrated hydrochloric acid and 50 ml distilled water. Stirring is continued for one hour. The 5-nitroso 6-hydroxy quinazolin (formula IV) is thus obtained as a yellow precipitate, which is washed with water, then dried.

1. distillationdistilled water
2. stirringStirring
3. waitis continued for one hour