Formaldehyde → HCID 19882360, compound

HRID 847154Notes

Reaction equation

HRID 847154 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[NH:10])=[O:9])=[CH:4][CH:3]=1.[NH:12]1[CH2:16][CH2:15][CH2:14][CH2:13]1.[CH2:17]=O>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[N:10][CH2:17][N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[O:9])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 31268PyrrolidineHCID 113222501-Bromo-4-(S-Methylsulfonimidoyl)Benzene

Product 1

HCID 19882360HCID 19882360, compound

Procedure

Following the procedures given for the Mannich reaction in Canadian Patent 1,102,803, the title compound is prepared from S-(4-bromophenyl)-S-methylsulfoximine, pyrrolidine, and 37% formaldehyde solution.

Workup

  1. customgiven for the Mannich reaction in Canadian Patent 1,102,803

Sources & evidence

ORD record
ord-797935855df14eeeb9949bf4dbc3d581
Source dataset
uspto-grants-1992_08
Patent number
US05140026

Reaction notes

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