Acetone → HCID 22706905, compound

Participants

Reaction Steps

Into a four-necked flask of 1 l capacity were charged 40.5 g (0.25 mol) of p-n-butylbenzaldehyde, 27.0 g (0.25 mol) of o-phenylenediamine, 28.6 g (0.23 mol) of sodium sulfite and 350 ml of dimethylformaldehyde, and a reaction was effected for 1 hour while refluxing the reaction solution. Then, 250 ml of water was added to the reaction mass, and the resulting mixture was cooled and filtered. The filter cake was washed with water to obtain the aimed 2-p-n-butylphenylbenzimidazole in an yield of 52.2 g (82.9%).

Provenance & Evidence