反应详情

5-Hydroxy-1-indanone (1.48 g), N-iodosuccinimide (2.25 g) and CH3CN (20 ml) were stirred at room temperature overnight. The solution was evaporated to dryness, slurried with EtOAc, then filtered. The filtrate was evaporated to dryness and the solid recrystallized from CH3CN affording the desired compound (0.92 g), m.p. 114°-15° C.

1. customThe solution was evaporated to dryness
2. filtrationfiltered
3. customThe filtrate was evaporated to dryness
4. customthe solid recrystallized from CH3CN affording the desired compound (0.92 g), m.p. 114°-15° C.