Tetrahydrofuran → HCID 178418348, compound

HRID 847341Notes

Reaction equation

HRID 847341 reaction equation
[CH3:1][Li:2].C1CCCCC1.[CH2:9]1[CH2:13][O:12][CH2:11][CH2:10]1>>[Li:2][CH3:1].[CH2:9]1[CH2:13][O:12][CH2:11][CH2:10]1.[Li:2][CH3:1]

Participants

5

Reactant 3

HCID 8028TetrahydrofuranHCID 8078CyclohexaneHCID 178418348HCID 178418348, compound

Product 2

HCID 178418348HCID 178418348, compoundHCID 178420698HCID 178420698, compound

Procedure

In a further experiment (see Table I - Exp. No. 3), an attempt to dissolve solid methyllithium with cyclohexane containing two equivalents of THF resulted in a sparingly soluble product (MeLi=0.20 M -THF/MeLi=18.5 mole ratio) which precipitated (clear solution=0.13 M ) overnight in the refrigreator at 0° C. In the final experiment (see Table I - Exp. No. 4) an attempt to dissolve solid methyllithium with toluene containing two equivalents of diethyl ether (Et2O) also resulted in a slightly soluble product. (MeLi=0.14 M - THF/MeLi=22.2 mole ratio.)

Sources & evidence

ORD record
ord-0278d8cd28ad44a1b314bc940594d498
Source dataset
uspto-grants-1992_08
Patent number
US05141667

Reaction notes

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