Glycolic Acid → HCID 19881208, compound

HRID 847358Notes

Reaction equation

HRID 847358 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[C:12]([OH:16])(=[O:15])[CH2:13][OH:14]>C(O)C>[Br:8][C:5]1[CH:6]=[CH:7][C:2]([O:14][CH2:13][C:12]([OH:16])=[O:15])=[C:3]([N+:9]([O-:11])=[O:10])[CH:4]=1

Participants

4

Reactant 2

HCID 757Glycolic AcidHCID 770041,4-Dibromo-2-nitrobenzene

Product 1

HCID 19881208HCID 19881208, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction between 28.1 g of 2,5-dibromonitrobenzene and 7.6 g of glycolic acid was carried out by heating in a 70% aqueous ethanol solution under alkaline conditions to give 19.3 g of 4-bromo-2-nitrophenoxyacetic acid as precipitated crystals.

Sources & evidence

ORD record
ord-9435d7768f4d4fcdb1dfd3bcf0b83898
Source dataset
uspto-grants-1992_08
Patent number
US05141935

Reaction notes

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