HCID 67916069, compound → HCID 136403387, compound

Participants

Reaction Steps

3 g of 5-(3-benzyloxy-1,1'-biphenyl-4-yl)-1H-pyrazol-4-yl-propionic acid hydrazide are dissolved with heating in isopropanol and hydrogenated over 10% palladium/charcoal. The catalyst is filtered off, the reaction mixture concentrated by evaporation and the concentrate allowed to stand for ca. 12 hrs. in a refrigerator. The title compound crystallises out as the dihydrochloride and is recovered by filtration: m.p.=138°-141° C.

Provenance & Evidence