Methyl iodide → HCID 19881133, compound

Participants

Reaction Steps

To a solution of 0.9 g of 5-(2-dimethylaminoethyl)-2-methyl-5,6,7,8-tetrahydro-4H-thieno[3,2-c]azepin-4-one in 30 ml of acetone was added 0.4 ml of methyl iodide at room temperature. After being allowed to stand 30 minutes, the precipitated crystals were collected by filtration and washed with acetone to give 1.1 g of N-[2-(5,6,7,8-tetrahydro-2-methyl-4-oxo-4H-thieno[3,2-c]azepin-5-yl)ethyl]-N,N-dimethylammonium iodide as white crystals, melting at 237°-239° C.

Provenance & Evidence