Hydrochloric Acid → HCID 9887011, compound

Participants

Reaction Steps

To a solution of 1.37 g (0.0041 mol) 2-benzylseleno-3-methoxybenzoyl chloride (prepared from 2-benzylseleno-3-methoxybenzoic acid and α,α-dichloromethyl ether in dichloromethane at room temperature) in 10 ml pyridine at 0° C. is added with stirring a solution of 0.38 g (0.0041 mol-0.37 ml) aniline. After stirring at room temperature for 18 hours the contents of the flask are poured onto 150 g ice and 50 ml 25% HCl and extracted. The organic phase is washed with 50 ml 10% NaHCO3 and twice with 100 ml portions of dichloromethane and 200 ml water, dried over sodium sulfate and the solvent removed in vacuum.

Provenance & Evidence