反应详情

750 ml of SOCl2 were added to 239.5 g (1 mole) of 3-chloro-4-trifluoromethoxy-benzamide and the mixture was slowly heated (according to the evolution of gas) to 85° C. The mixture was then fractionally distilled and 189 g of product having a boiling point at 13 mbar of 96° C. and a melting point of 38° to 40° C. were obtained. This corresponds to a yield of 85% of theory.

1. temperaturethe mixture was slowly heated (
2. customto 85° C
3. distillationThe mixture was then fractionally distilled
4. customat 13 mbar of 96° C.
5. customa melting point of 38° to 40° C. were obtained