反应详情

温度

80 °C

A mixture of ethylenediamine (308 g) and methyl isobutyrate (87.15 g) was stirred at 80° C. for 15 hours. After removal of excess ethylenediamine under reduced pressure, the residue was dissolved in ethyl acetate (100 ml). Insoluble material was filtered off and the filtrate was concentrated and distilled to give N-isobutyrylethylenediamine (84.45 g).

1. customAfter removal of excess ethylenediamine under reduced pressure
2. dissolutionthe residue was dissolved in ethyl acetate (100 ml)
3. filtrationInsoluble material was filtered off
4. concentrationthe filtrate was concentrated
5. distillationdistilled