Ethylenediamine → N-(2-Aminoethyl)-2-methylpropanamide

Participants

Reaction Conditions

Reaction Steps

A mixture of ethylenediamine (308 g) and methyl isobutyrate (87.15 g) was stirred at 80° C. for 15 hours. After removal of excess ethylenediamine under reduced pressure, the residue was dissolved in ethyl acetate (100 ml). Insoluble material was filtered off and the filtrate was concentrated and distilled to give N-isobutyrylethylenediamine (84.45 g).

Provenance & Evidence