Methanol → HCID 12548239, compound

HRID 847579Notes

Reaction equation

HRID 847579 reaction equation
O.O.O.O.O.O.O.O.O.[S-2:10].[Na+].[Na+].Br[CH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.CO>O1CCCC1>[C:16]1([CH2:15][CH2:14][S:10][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 7666Phenethyl bromideHCID 73972Sodium sulfide nonahydrate

Product 1

HCID 12548239HCID 12548239, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A solution of 7.65 g (32 mmol) of sodium sulfide nonahydrate and 8.7 ml (64 mmol) of 2-bromoethylbenzene in 150 ml of 1:1 tetrahydrofuran:methanol was heated at reflux under inert atmosphere. After 24 h, the solution was allowed to cool and concentrated in vacuo to give the crude desired compound.

Workup

  1. temperatureat reflux under inert atmosphere
  2. temperatureto cool
  3. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-e7ad56166dfa4106b274f1603a895117
Source dataset
uspto-grants-1992_08
Patent number
US05142056

Reaction notes

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