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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 847615Generated: October 31, 2026

Carbodiimide → 2,4-Bis-(N-((p-toluenesulfonyl)valinyl)amino)-1,5-diphenyl-3-hydroxypentane

https://huagongshe.com/reaction/847615

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbodiimideHCID 160435—
ReactantTosyl valineHCID 2249310—
Reactant2-Amino-4-(N-((p-toluenesulfonyl)valinyl)amino)-1,5-diphenyl-3-hydroxypentane HydrochlorideHCID 22845588—
Product2,4-Bis-(N-((p-toluenesulfonyl)valinyl)amino)-1,5-diphenyl-3-hydroxypentaneHCID 22845570—

Reaction Steps

According to the carbodiimide coupling procedure of Example 55, N-(p-toluenesulfonyl)valine was coupled to the resultant compound of Example 112 to give the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05142056
Source datasetuspto-grants-1992_08
ORD IDord-40610826b2664dce9d71a7af0b9b4dd0
Source noteuspto-grants-1992_08