反应详情

50 ml of dichloromethane was added to 7.9 g of N-(1,2,2,2-tetrachloroethyl)-2-acetoxybenzamide. 1.3 g of ethyl mercaptan was add to the solution under stirring and then 2.0 g of triethylamine was added dropwise thereto at 10°-15° C. After effecting the reaction at room temperature for one hour, water was added thereto and the solution was allowed to stand. Then the dichloromethane layer was separated out, dried with unhydrous sodium sulfate and concentrated to obtain 7.0 g of N-(1-ethylthio-2,2,2-trichloroethyl)-2-acetoxybenzamide as white crystals.

1. customat 10°-15° C
2. customthe reaction at room temperature for one hour
3. customThen the dichloromethane layer was separated out
4. dry with materialdried with unhydrous sodium sulfate
5. concentrationconcentrated