Hydrochloric Acid → HCID 12940152, compound

HRID 848059Notes

Reaction equation

HRID 848059 reaction equation
[CH:1]([S:4][CH:5]([NH:10][C:11](=[O:22])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18]C(=O)C)[C:6]([Cl:9])([Cl:8])[Cl:7])([CH3:3])[CH3:2].Cl>C(O)C>[CH:1]([S:4][CH:5]([NH:10][C:11](=[O:22])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[OH:18])[C:6]([Cl:8])([Cl:7])[Cl:9])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20566248HCID 20566248, compound

Product 1

HCID 12940152HCID 12940152, compoundYield 94.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.2 g of N-(1-iso-propylthio-2,2,2-trichloroethyl)-2-acetoxybenzamide, 30 ml of ethanol and 0.5 ml of 35% hydrochloric acid were mixed together and the reaction was effected while stirring under reflux for two hours. The solvent was distilled off, and the contents were washed with water and dried to obtain 2.7 g of N-(1-iso-propylthio-2,2,2-trichloroethyl)-2-hydroxybenzamide as white crystals.

Workup

  1. temperatureunder reflux for two hours
  2. distillationThe solvent was distilled off
  3. washthe contents were washed with water
  4. customdried

Sources & evidence

ORD record
ord-56f7bb581b564a3bb931d05bd7dab494
Source dataset
uspto-grants-1981_10
Patent number
US04294835

Reaction notes

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