3-Chloro-N,N-dimethyl-1-propanamine → N,N-Dimethyl-3-{[oxo(phenyl)(thiophen-2-yl)-lambda~6~-sulfanylidene]amino}propan-1-amine

Participants

Reaction Steps

In a manner analogous to that described in Example 1, Stage 3, by the reaction of phenyl-(2-thienyl)-sulphoximide with 3-dimethylaminopropyl chloride, there is obtained, in a yield of 38% of theory, N-(3-dimethylaminopropyl)-S-phenyl-S-(2-thienyl)-sulphoximide, the fumarate of which, after recrystallisation from ethyl acetate/isopropanol, melts at 125° C.

Provenance & Evidence